@article{Charles2021,

title = {Ticks and Tick-Borne Diseases in Central America and the Caribbean: A One Health Perspective},

author = {Roxanne A. Charles and Sergio Bermúdez and Pavle Banović and Dasiel Obregon and Adrian Alberto Díaz-Sánchez and Belkis Corona-González and Eric Marcel Charles Etter and Islay Rodríguez González and Abdul Gaffar and Abdul Jabbar and Sara Moutailler and Alejandro Cabezas-Cruz},

editor = {Mária Kazimírová},

url = {https://www.mdpi.com/2076-0817/10/10/1273},

doi = {https://doi.org/10.3390/pathogens10101273},

year  = {2021},

date = {2021-09-27},

journal = {Pathogens},

volume = {10},

number = {10},

abstract = {Ticks have complex life cycles which involve blood-feeding stages found on wild and

domestic animals, with humans as accidental hosts. At each blood-feeding stage, ticks can transmit

and/or acquire pathogens from their hosts. Therefore, the circulation of tick-borne pathogens (TBPs),

especially the zoonotic ones, should be studied in a multi-layered manner, including all components

of the chain of infections, following the ‘One Health’ tenets. The implementation of such an approach

requires coordination among major stakeholders (such as veterinarians, physicians, acarologists,

and researchers) for the identification of exposure and infection risks and application of effective

prevention measures. In this review, we summarize our current knowledge on the epidemiology of

tick-borne diseases in Central America and the Caribbean and the challenges associated with the

implementation of ‘One Health’ surveillance and control programs in the region.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Stankov2021,

title = {O značaju higijenskih mera u suzbijanju infektivnih bolesti koje se prenose respiratornim putem},

author = {Srđan Stankov},

doi = {https://doi.org/10.5937/smclk2-32327},

year  = {2021},

date = {2021-06-23},

journal = {Srpski medicinski časopis Lekarske komore},

volume = {2},

number = {1},

pages = {11-15},

publisher = {Lekarska komora},

abstract = {Zarazne bolesti su postojale u obliku epidemija tokom istorije čovečanstva, a patogeni mikroorganizmi su dugo bili smatrani odgovornim za njihovo pojavljivanje. Međutim, takozvani biološki agensi akutnih zaraznih bolesti nisu njihovi stvarni uzroci, već samo katalizatori već postojećih patoloških procesa. Otuda ekstremna varijabilnost lokacije i intenziteta patoloških procesa sa istim biološkim uzročnikom kod različitih jedinki vrste domaćina. Patogenost i virulencija mikroorganizama nisu njihova vlastita i nepromenljiva svojstva, već su samo rezultat patogenosti neživih faktora životne sredine koji deluju na domaćina i koji obično ostaju van fokusa medicinskih istraživanja. Pitanje od glavne praktične važnosti, kako da sprečimo pojavu zaraznih bolesti, daje nam istorija. U prošlosti su mnoge higijenske mere bile dovoljne da se većina zaraznih bolesti svede na neznatnu pojavu. Do sada je društvo puno uradilo na higijenskim standardima čvrstih i tečnih materija u našem okruženju. Međutim, briga o higijeni atmosfere i dalje je prilično nerazvijena i zanemarena. Danas se atmosfera neprekidno i sistematski zagađuje određenim gasovima, parama kao i česticama. Direktni rezultat ovakog stanja razvoja higijenske prakse je da su danas jedina vrsta epidemija koje pogađaju opštu populaciju epidemije koje se šire atmosferom, tj. respiratorne epidemije. Da bi se trajno eliminisala dalja mogućnost respiratornih epidemija, neophodno je uvesti trajne i sistematske mere za održavanje higijene atmosfere ljudskih naselja.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Banović2021c,

title = {A One Health approach to study the circulation of tick-borne pathogens: A preliminary study},

author = {Pavle Banović and Adrian Alberto Díaz-Sánchez and Clemence Galon and Angélique Foucault-Simonin and Verica Simin and Dragana Mijatović and Luka Papić and Alejandra Wu-Chuang and Dasiel Obregon and Sara Moutailler and Alejandro Cabezas-Cruz },

doi = {https://doi.org/10.1016/j.onehlt.2021.100270},

year  = {2021},

date = {2021-06-01},

journal = {One Health},

abstract = {Tick-borne pathogens (TBPs) have complex life cycles involving tick vectors and vertebrate hosts. However, there is limited empirical evidence on the zoonotic circulation of TBPs. In this study, we used a One Health approach to study the possible circulation of TBPs in ticks, animals and humans within a rural household in the foothills of the Fruška Gora mountain, northern Serbia. The presence of TBP DNA was assessed using microfluidic PCR (25 bacterial species, 7 parasite species, 5 bacterial genera, 3 parasite genera) in animal, human and tick samples and the presence of tick-borne encephalitis virus (TBEV) RNA was screened for using RT-qPCR on tick samples. In addition, Lyme borreliosis serology was assessed in patient sera. Rhipicephalus sanguineus and Ixodes ricinus ticks were identified on dogs and Haemaphysalis punctata was identified on house walls. Rickettsia helvetica was the most common pathogen detected in pooled R. sanguineus and I. ricinus tick samples, followed by Hepatozoon canis. None of the H. punctata tick samples tested positive for the presence of TBPs. Anaplasma phagocytophilum and Rickettsia monacensis were the most frequent pathogens detected in dogs, followed by Rickettsia felis, whereas Anaplasma bovis was the only pathogen found in one of the goats tested. None of the human blood samples collected from family members tested positive for the presence of TBPs. Although microfluidic PCR did not detect Borrelia sp. in any of the tested tick or blood samples, a family member with a history of Lyme disease was seropositive for Borrelia burgdorferi sensu lato (s.l.). We conclude that, despite the presence of TBPs in tick and vertebrate reservoirs, there is no evidence of infection with TBPs across various components of the epidemiological chain in a rural Fruška Gora household.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Banović2020,

title = {Humans infested with Ixodes ricinus are exposed to a diverse array of tick-borne pathogens in Serbia},

author = {Pavle Banović, Adrian Alberto Díaz-Sánchez, Clemence Galon, Verica Simin, Dragana Mijatović, Dasiel Obregón, Sara Moutailler, AlejandroCabezas-Cruz

},

url = {https://www.sciencedirect.com/science/article/abs/pii/S1877959X20304799?fbclid=IwAR3nbGgtSfPEXPX54Vr7DTBcHI_KlKPum63yjfSznOTm7NFkh7PyqLzerTs},

doi = {https://doi.org/10.1016/j.ttbdis.2020.101609},

year  = {2020},

date = {2020-11-24},

journal = {Ticks and Tick-borne Diseases},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Verica2020,

title = {Borellia burgdorferi infection in removed ticks and anti-borrelia antibodies in infested patients admitted to the Pasteur Institute, Novi Sad},

author = {Simin Verica and Dragana Mijatović and Snežana Tomanović and Milan Miljević and Borislav Čabrilo and Bogdan Ivana and Pavle Banović},

doi = {10.2298/VETGL200527008S},

year  = {2020},

date = {2020-10-03},

journal = {Veterinarski glasnik},

abstract = {Introduction. The primary objectives of this study were (1) to determine the presence of Borrelia burgdorferi infection in ticks removed from patients for the purpose of singling out sites with increased risk of Lyme borreliosis, and (2) to determine the presence of IgM and/or IgG antibodies against B.  burgdorferi  sensu lato (s. l.) complex in sera of patients who had ticks removed 

Materials  and  Methods.  From  108  ticks  removed  from  patients,  all  were  examined zoologically and a sub-sample of 91 ticks was tested using PCR analysis to determine the presence of DNA indicating B. burgdorferi infection. To detect anti-Borrelia IgM and/or IgG antibodies in 61 patients bitten by ticks, we used line recombinant immunoblot test.

Results and Conclusions. The most common tick identified was Ixodes ricinus. B. burgdorferi s. l. was present in 37 of 91 tested ticks (40.7%). Seroconversion against B. burgdorferi s. l. antigen was detected in 12 of 61 patients (19.7%). Most of the infected ticks were from the province of Vojvodina (11 municipalities), with the city of Novi Sad proving to be the site with the highest number of infected ticks, 6 in total. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Gordana2020,

title = {Molecular evaluation of chronic restrain stress in mice model of non metastatic fibrosarcoma},

author = {Smieško Gordana and Banović Pavle and Gusman Vera and Simin Verica and Anca Maria Cimpean and Dušan Lalošević},

url = {https://link.springer.com/article/10.1007/s10735-020-09886-5},

doi = {https://doi.org/10.1007/s10735-020-09886-5},

year  = {2020},

date = {2020-06-18},

journal = {Journal of Molecular Histology},

abstract = {Chronic stress is regarded as a significant factor in the etiology of the many diseases. Numerous methods have been developed through which the effect of chronic stress is examined. The aim of this study is to demonstrate the new experimental model for analysis of immuno-suppression induced by chronic restraint stress, through challenge with conditionally tumorigenic cell line BHK-21/C13. 20 male NMRI mice were randomly divided into 2 groups—control and experimental. Each mouse was subcutaneously inoculated with BHK-21/C13 cells. Stress in the experimental group was induced for 20 days. After the experiment, tumor masses were removed, and analyzed using histology and immunohistochemistry techniques. We found a statistically significant difference (p = 0.034) in tumor expression and tumor volumes (p = 0.0061) between groups, as well as in immunopositivity on Ki67, cytochrome C and matrix metalloproteinase 9. Absence of immune infiltrate was noticed in experimental, and the presence of inflammatory infiltrate at tumor invasion front in control group.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}