@article{Smieško2023,

title = {Povećana učestalost urinarnih infekcija izazvanih rodom Enterococcus kod pacijenata COVID-19 bolnice Kliničkog centra Vojvodine},

author = {Gordana Smieško and Marija Baros Brkljaca and Pavle Banović},

doi = {10.5937/pomc19-37033},

year  = {2023},

date = {2023-01-20},

journal = {PONS - Medicinski časopis},

abstract = {Cilj. Ispitivanje učestalosti izolata različitih uropatogena kod pacijenata COVID-19 bolnice ,,Mišeluk’’ u poređenju sa pacijentima iz ne-COVID-19 zone Kliničkog Centra Vojvodine (KCV). 

Metode. Za potrebe ovog istraživanja sakupljene su informacije o izolatima iz urina upućenih iz COVID-19 bolnice i ne-COVID-19 zona KCV u tromesečnom periodu, pri čemu su uzorci iz ne-COVID-19 zone KCV služile kao kontrola.

Rezultat.: Od 449 nalaza pacijenata iz COVID-19 bolnice, najčešći nalaz su pripadnici roda Enterococcus, (216/449; 48,10%), koji su u najvećem broju slučajeva uzrokovali IUT kod žena (127/216;58,79%). Drugi po učestalosti uzročnik IUT u COVID-19 bolnici je Klebsiella pneumoniae (85/449;

18,93%). Od 913 nalaza pacijenata iz ne-COVID-19 klinika KCV, najčešći uzročnik IUT je Escherichia coli (249/913; 27,27%), i to dominantno kod žena (199/249;79,91%, (χ2 (1) = 49,042; p < 0,00001)). Drugi po učestalosti uzročnki IUT su pripadnici roda Enterococcus, (216/913; 23,65%), bez

značajne razlike u distribuciji među polovima (χ2 (1) = 0,0833; p = 0,847).

Zaključak. Najčešći uzročnici IUT u COVID-19 bolnici KCV su pripadnici roda Enterococcus i Klebsiella pneumoniae sa gotovo ravnomernom raspodelom među polovima. Uočena je statistički značajna razlika u učestalosti različitih izazivača IUT kod pacijenata COVID-19 bolnice naspram

ne-COVID-19 klinika KCV. Ovi rezultati mogu biti značajni za određivanje empirijske terapije kod pacijenata COVID-19 bolnice KCV, kao i pri planiranju procedura za redukciju intrahospitalih infekcija.},

keywords = {},

pubstate = {forthcoming},

tppubtype = {article}

}

@article{Banović2023,

title = {Emerging tick-borne spotted fever group rickettsioses in the Balkans},

author = {Pavle Banović and Adrian Alberto Díaz-Sánchez and Angélique Foucault-Simonin and Lourdes Mateos-Hernandez and Alejandra Wu-Chuang and Clemence Galon and Verica Simin and Dragana Mijatović and Ivana Bogdan and Belkis Corona-González and Liani 

 Coronado Báez and Joanna Kulisz and Aneta Woźniak and Zbigniew Zając and Dasiel Obregón and Sara Moutailler and Alejandro Cabezas-Cruz},

doi = {https://doi.org/10.1016/j.meegid.2022.105400},

year  = {2023},

date = {2023-01-05},

urldate = {2023-01-05},

journal = {Infection, Genetics and Evolution},

volume = {107},

abstract = {The impact of tick-borne pathogens (TBPs) on human health has increased in the last decades, since the incidence of emerging and re-emerging infectious and zoonotic tick-borne diseases has increased worldwide. Tick-borne rickettsiae of the Spotted Fever group (SFGR) are considered as emerging pathogens that can infect humans and cause a variety of non-specific clinical symptoms. Here, we report nine cases of atypical tick-borne diseases (9/460; 1.95%) that occurred over a period of four months (from 15 April 2021 to 16 August 2021) in Serbia, from which five cases were classified as confirmed SFGR infection, two cases as probable SFGR infection and two cases as suspected SFGR infection. Within cases of confirmed SFGR infection, R. helvetica was detected as the causative agent in two cases. The most common clinical finding was non-expanding persistent circular redness, followed by eschar and enlargement of regional lymph nodes, and pain at lesion site. Rickettsia outer membrane protein B (ompB) and citrate synthase (gltA) gene fragments were amplified from clinical samples and ticks attached to patients and IgG reacting with Rickettsia conorii antigen were detected in sera samples of patients, which are highly suggestive of exposure to SFGR. Surveillance and monitoring of rickettsial diseases in Serbia should continue and extended to new areas due to the increasing trend of clinical infections caused by SFGR in the country.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Dragonjić2022,

title = {Fatal Case of Imported Tick-Borne Encephalitis in South Serbia},

author = {Lidija Popović Dragonjić and Miodrag Vrbić and Aleksandar Tasić and Verica Simin and Ivana Bogdan and Dragana Mijatović and Alejandro Cabezas-Cruz and Pavle Banović},

editor = {Harunor Rashid},

doi = {https://doi.org/10.3390/tropicalmed7120434},

year  = {2022},

date = {2022-12-13},

journal = {Tropical Medicine and Infectious Disease},

volume = {7},

number = {434},

issue = {12},

abstract = {Tick-borne encephalitis (TBE) is vaccine-preventable neglected zoonotic neuroinvasive disease, caused by tick-borne encephalitis virus (TBEV). Many of the Central and Eastern European countries are affected by TBE, which is often poorly perceived by tourists visiting endemic territories. Here we are reporting a fatal case of imported TBE in Serbian resident who was exposed to a tick bite during a visit to Switzerland.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Banović2022c,

title = {Differential detection of tick-borne pathogens in human platelets and whole blood using microfluidic PCR},

author = {Pavle Banović and Elianne Piloto-Sardiñas and Dragana Mijatović and Angélique Foucault-Simonin and Verica Simin and Ivana Bogdan and Dasiel Obregon and Lourdes Mateos-Hernández and Sara Moutailler and Alejandro Cabezas-Cruz},

doi = {https://doi.org/10.1016/j.actatropica.2022.106756},

year  = {2022},

date = {2022-11-23},

journal = {Acta Tropica},

abstract = {The tick-borne pathogens (TBPs) with adhesive phenotype can use platelets for dissemination and colonization of distant tissues and organs, and it has been shown that they can be found concentrated in the platelet fraction of blood. This study shows the differential presence of TBPs in samples of human platelet fraction (n = 68), whole blood samples (n = 68) and ticks collected (n = 76) from the same individuals, using an unbiased high-throughput pathogen detection microfluidic system. The clinical symptoms were characterized in enrolled patients. In patients with suspected TBP infection, serological assays were conducted to test for the presence of antibodies against specific TBPs. Tick species infesting humans were identified as Ixodes ricinus, Dermacentor reticulatus, and Haemaphysalis punctata. Eight patients developed local skin lesions at the site of the tick bite including non-specific lesions, itching sensation at the lesion site, and eschar. Most common TBPs detected in platelet fraction were Borrelia spielmanii and Rickettsia sp., followed by Borrelia afzelii and Anaplasma phagocytophilum. Multiple infections with three TBPs were detected in platelet fraction. In whole blood, most common TBPs detected were Anaplasma spp. and A. phagocytophilum, followed by Rickettsia spp. and B. afzelii. In ticks, the most common TBP detected was Rickettsia spp., followed by Borrelia spp. and Anaplasma spp. Overall, nine different pathogens with variable prevalence were identified using species-specific primers, and the most common was Rickettsia helvetica. In three patients, there were no coincidences between the TBPs detected in whole blood and tick samples. Only in one patient was detected A. phagocytophilum in both, whole blood and tick samples. These results suggest the unequal detection of TBPs in whole blood, platelet fraction and ticks collected, from the same individual. The results justify the use of both whole blood and platelet fraction for molecular diagnosis of TBPs in patients.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jakimovski2022,

title = {Mediterranean spotted fever-like illness caused by Rickettsia sibirica mongolitimonae, North Macedonia, June 2022},

author = {Dejan Jakimovski and Sofija Mateska and Verica Simin and Ivana Bogdan and Dragana Mijatović and Agustín Estrada-Peña and Lourdes Mateos-Hernández and Angélique Foucault-Simonin and Sara Moutailler and Alejandro Cabezas-Cruz and Pavle Banović},

doi = {https://doi.org/10.2807/1560-7917.ES.2022.27.42.2200735},

year  = {2022},

date = {2022-10-21},

journal = {Eurosurveillance},

volume = {27},

issue = {42},

abstract = {Mediterranean spotted fever (MSF)-like illness is tick-borne disease caused by Rickettsia sibirica mongolitimonae, an obligate intracellular bacterium, most probably transmitted by ticks of the genus Rhipicephalus and genus Hyalomma. While cases of MSF, which are caused by Rickettsia conorii, are frequently detected in endemic areas of Europe around the Mediterranean Basin, MSF-like illness is reported sporadically in different European and African countries. Here we present a case of MSF-like illness caused by R. sibirica mongolitimonae in a female patient after a bite from a Hyalomma tick in North Macedonia.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}